Pterostilbene has seen a steady rise in popularity in the recent past. The compound has become a staple ingredient in many drugs and supplements due to its numerous health benefits.
In this article, we introduce pterostilbene and focus on its perceived pharmacological applications. We’ll also attempt to demystify some of the frequently asked questions about the compound, including its relationship with resveratrol, potential side effects, and dosing recommendations.
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Introducing Pterostilbene
Pterostilbene is an organic polyphenol, a class of naturally occurring bioactive chemicals in plants. These compounds collectively protect plants from various diseases.
Pterostilbene belongs to a special category of polyphenols known as stilbenes. The chemical assumes two different forms, namely trans-pterostilbene and cis-pterostilbene.
Emerging research indicates that pterostilbene may offer certain pharmacological benefits to humans. Pterostilbene benefits are primarily due to its antioxidant and anti-inflammatory properties. But as you shall find, this compound also possesses certain abilities that make it a potential treatment for a broad spectrum of health issues.
Difference Between Pterostilbene and Resveratrol
Pterostilbene and resveratrol are structurally and chemically related. That explains the common confusion between the two organic compounds.
However, pterostilbene is more like a structural isomer of resveratrol. It differs from its parent chemical in its higher bioavailability. Many findings have demonstrated that pterostilbene can enter the bloodstream four times faster than resveratrol.
Pterostilbene also enjoys a longer half-life of up to 105 minutes than resveratrol’s 14 minutes. Besides, the compound is less prone to damage by environmental elements.
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Health Benefits of Pterostilbene
1. Attenuating Oxidative Stress
Oxidative stress is a phenomenon whereby free radicals accumulate in or around cells in the body. Free radicals are unstable oxygen-containing molecules that result from various biological processes. A steady build-up of free radicals may trigger oxidative stress, consequently leading to cell and tissue damage.
Studies have shown that pterostilbene may mitigate particulate matter-induced free radicals. Therefore, the compound might guard against various chronic ailments.
2. Preventing Premature Aging
Pterostilbene may not have direct effects in terms of delaying the aging process. However, ongoing research indicates that the compound may combat premature aging indirectly.
For instance, the antioxidant properties of pterostilbene speak to its ability to counter the premature degeneration of cells, tissues, and organs. Its ability to promote mitochondrial functions might further help to fight old age at the cellular level by providing the energy required for optimal performance of organs and tissues.
3. Alleviating Inflammation
Nearly all polyphenols boast incredible anti-inflammatory properties, and pterostilbene is no exception.
Pterostilbene alleviates inflammation by countering the production of proteins, such as chemokines and cytokines, that aid the transmission of inflammatory signals throughout the body.
4. Fighting Cancer
Most cancers produce inflammation as a core symptom. Consequently, the fact that pterostilbene may relieve inflammation speaks to its anti-carcinogenic properties. Besides, the compound’s ability to attenuate oxidative stress may reduce the proliferation of unhealthy or cancerous cells.
Existing research indicates that pterostilbene may fight various types of cancer. The chemical has especially demonstrated efficacy against breast cancer, prostate cancer, and colon cancer.
5. Treating Diabetes
Diabetes is a leading lifestyle disease responsible for millions of deaths around the world annually. Fortunately, it’s reassuring to know that increasing your uptake of pterostilbene supplements may treat and even prevent the illness.
Pterostilbene’s anti-diabetic effects have much to do with its ability to decrease blood glucose levels while improving insulin sensitivity. The compound may also alleviate inflammation associated with obesity, which is a major risk factor for diabetes.
6. Protecting Vital Organs
There’s abundant research indicating that pterostilbene may protect all vital organs, including the heart, brain, and eyes. The compound may improve cardiovascular health by accelerating lipid metabolism and lowering the levels of LDL (bad) cholesterol.
Some studies indicate that pterostilbene might improve vision by protecting corneal cells from oxidative damage. Further research cites its ability to enhance all aspects of cognitive performance, including memory, attention, and learning abilities.
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Pterostilbene Side Effects
Most pterostilbene-based studies haven’t revealed any significant adverse events. However, dietary pterostilbene may trigger certain negative reactions, such as gastrointestinal distress. Symptoms here can range from nausea and vomiting to diarrhea, stomach upset, and abdominal pains.
Pterostilbene might also be a blood thinner due to its powerful anti-thrombotic properties. It’s prudent to talk to your doctor before taking pterostilbene supplements if you’re presently on blood thinning medications like aspirin or warfarin.
Other potential adverse effects of pterostilbene include allergic reactions (such as rash or difficulty breathing) and negative interactions with other medications (particularly coagulants and antiplatelets). The risk and severity of side effects are higher for new users and/or those who consume significantly high pterostilbene doses.
Recommended Pterostilbene Dosage
Currently, there’s no consensus dosage for pterostilbene. Serving amounts depend on your metabolic rate and the reasons for administering the drug.
However, a daily dosage of 200 – 700 milligrams has demonstrated the highest efficacy levels among many users.
Natural Pterostilbene Sources
Pterostilbene occurs naturally in blueberries, cranberries, grapes, and Japanese knotweed. The chemical is also considerably high in cocoa powder and, by extension, chocolate products.
Various nuts contain small amounts of pterostilbene, too. They include almonds, peanuts, pistachios, and pecans.
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Summary
Pterostilbene boasts powerful healing benefits. The compound also has a relatively high safety profile.
However, always consult a healthcare professional before integrating pterostilbene into your wellness routine. Be sure to also stick to the product’s dosage guidelines.
